Background:

This gene encodes a member of the class I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein is a selenocysteine-containing flavoenzyme that maintains thioredoxins in a reduced state, thereby playing a key role in regulating the cellular redox environment. Mammals have three related thioredoxin reductases. This gene encodes a mitochondrial form important for scavenging of reactive oxygen species in mitochondria.

Applications:

WB, IHC

Name of antibody:

TXNRD2

Immunogen:

Synthesized peptide derived from Internal of human TRXR2.

Full name:

thioredoxin reductase 2

Synonyms：

TR; TR3; SELZ; TRXR2; TR-BETA

SwissProt:

Q9NNW7

IHC positive control:

Human breast carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

57 kDa

WB Positive control:

HT29 cells lysate

WB Recommended dilution:

500-3000